6th Workshop on Computation of Biochemical Pathways
and Genetic Networks

BIOQUANT
Heidelberg
September 16-17, 2010




Program


Thursday, 16th

08:30 - 09:00 Registration
09:00 - 09:15 Welcome and Organisatorial Information

09:15 - 12:15 Session I: Parameter estimation in fuzzy/noisy systems


09:15 - 10:00 Linking systems biology models to data: a stochastic kinetic model of p53 oscillations (Richard Boys)
10:00 - 10:45 Identifiability Analysis and Experimental Design for Dynamical Models in Systems Biology (Jens Timmer)
10:45 - 11:15 Coffee break
11:15 - 12:00 On Parameter Estimation in Complex Differential Equations (Johannes Schlöder)
12:00 - 12:15 General discussion of session

12:15-14:00 Lunch break

14:00 - 16:30 Session II: Global sensitivity analysis


14:00 - 14:45 Global sensitivity analysis for systems biology: an overview of current methods and applications (Maria Rodriguez)
14:45 - 15:30 Global sensitivity analysis of ODEs via solution of the associated Fokker-Planck equation (Wilhelm Huisinga)
15:30 -16:00 Coffee break
16:00 -16:45 Nonlinear Bionetwork Structure Inference Using the Random Sampling-High Dimensional Model Representation (RS-HDMR) Algorithm (Xiao-Jiang Feng)
16:45 - 17:30 General discussion of the session

Workshop dinner


Friday, 17th


09:00 - 12:30 Session III: New approaches to spatial modeling


09:00 - 09:45 Towards modeling of spatial dynamic systems based on microscopy images (Szymon Stoma)
09:45 - 10:30 Space, geometry, motion and interactions in modeling biological systems: the BioShape approach (Luca Tesei)
10:30 - 10:50 Coffee break
10:50 - 11:35 Hierarchic stochastic modelling - a new concept based on emergent behavior of biomolecules (Kevin Thurley)
11:35 - 12:20 Efficient modeling of the spatial dynamics of tissues by automated transformation of graphical cell behavioral models into multi-agent based simulations (Niels Grabe)
12:20 - 12:30 General discussion of session

12:30 - 14:00 Lunch break

14:00 - 17:00 Session IV: Computation of microRNA regulatory networks


14:00 - 14:45 Studying the microRNA induced regulatory network (Sanghamitra Bandyopadhyay)
14:45 - 15:30 Integrating microRNA expression data and other sources in module network reconstruction (Eric Bonnet)
15:30 - 16:00 Coffee break
16:00 - 16:45 The microRNA regulatory network: Challenges in mapping a new layer of gene regulation (Gabriele Sales)
16:45 - 17:00 General discussion of session

17:00 End of workshop